Enabling Protein Degradation Drug Discovery

DUBtoolkit

A proprietary tool to support the design and development of regulators of novel deubiquitylase (DUB) enzyme inhibitors:

An ever increasing amount of data is entering the public domain and one of the challenges is to extract information that has the potential to support and inform compound design from these diverse data sources. A further key challenge is how to integrate and interpret these different sources of information in a way that provides insight into the design of novel compounds and drug leads.

Our solution is the DUBtoolkit™, a continuously evolving knowledge base and associated set of data-mining tools which captures relationships between deubiquitylase (DUB) enzymes using structural, genomic, biochemical and biological data in a way that has been optimised for exploitation by our medicinal and computational chemists in the design of novel compounds.

If you would like to learn more about how we can use our DUBtoolkit™ as part of a Collaborative Drug Discovery partnership please contact us at partnerships@ubiquigent.com.