Enabling Protein Degradation Drug Discovery

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HEK293 cell lysate (IL-1 stimulated)

Posted on December 14th, 2012 in
HEK293 Cell Lysate (IL-1 stimulated) may be used to demonstrate the ability of  ubiquitin binding domain proteins (Optineurin and NEMO) to capture polyubiquitylated proteins including IL-1 receptor-associated kinase 1 (IRAK1) (Windheim et al. 2008). Reference:Windheim M, Stafford M, Peggie M, Cohen… Read more